BDBM50334268 CHEMBL1642655::CHEMBL2205637::N-(6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl)-4-tert-butylbenzamide

SMILES CC(C)(C)c1ccc(cc1)C(=O)Nc1cn2cc(ccc2n1)-n1ccnc1

InChI Key InChIKey=SMJAMOAYGIVKRI-UHFFFAOYSA-N

Data  23 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334268   

TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50334268(CHEMBL1642655 | CHEMBL2205637 | N-(6-(1H-imidazol-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of ASK1 assessed as phosphorylated fluorescent peptide by mobility shift assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50334268(CHEMBL1642655 | CHEMBL2205637 | N-(6-(1H-imidazol-...)
Affinity DataIC50:  14nMAssay Description:Competitive inhibition of human recombinant N-terminal FLAG-tagged ASK1 expressed in baculovirus infected Sf2 cells after 60 mins by scintillation co...More data for this Ligand-Target Pair